Anchored Multiplex PCR (AMP™) is a novel technology to prepare target-enriched libraries from both RNA and DNA inputs for gene rearrangement detection and characterization by next-generation sequencing (NGS). AMP™ enriches for target fragments by PCR using an adapter that is ligated at random locations and target-specific primers. This method of library preparation confers numerous advantages over amplicon-based library construction in both the downstream data analysis as well as the scalability of translocation detection assays.
In this webinar, Dr. Kudlow discussed catalog and custom Archer™ products built upon the AMP™ technology and reviewed the scope and power of the data generated with this technology.
Brian Kudlow is a Group Lead and Senior R&D Scientist at Enzymatics, leading the development of next-generation sequencing assays for the detection of cancer-associated genomic translocations, mutations and copy number variations. Dr. Kudlow earned undergraduate degrees in mathematics and computer science and a PhD in molecular and cellular biology. He has worked in several areas of biology, including cell signaling, microRNA genetics and biochemistry, and more recently, high-throughput screening and diagnostics development.
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