Archer Analysis

Powerful NGS Bioinformatics

Archer® Analysis is a bioinformatics platform that performs automated processing of sequencing data generated from all Archer FusionPlex® (RNA), VariantPlex™ (DNA), Reveal ctDNA™, and Immunoverse™ (RNA) assays. This purpose-built software detects gene fusions, isoforms, single-nucleotide polymorphisms (SNPs), insertions/deletions (indels), copy number variations (CNVs) and expression patterns and provides visual, tiered results for accurate, clear mutation reporting. Analysis performs all secondary analysis, and many tertiary analysis step with annotations from the Archer Quiver™ Fusion Database, as well as sources such as Ensembl VEP, Clinvar, and COSMIC.
For Research Use Only. Not for use in diagnostic procedures.

Automated & Intuitive

Archer Analysis uses sequencing data from either Illumina® or Ion Torrent™ sequencing platforms, automating analysis with no need for programming expertise. Your results are presented in an easy-to-read, high-level summary that shows all fusions, CNVs, variants and complex mutations detected in your sample.

Archer Analysis also cross-references the Archer Quiver database of known fusions and reports fusions that are already published in the literature so you can distinguish known from novel fusions in your sample.

 

Archer Analysis provides in-depth data analysis and interpretation, including:

Archer Analysis was designed not only for intuitive data analysis and reporting, but also to meet your lab's specific IT, security and cost requirements. There is full transparency, including detailed processing logs. The software is available to download and install on your own server, and also as a cloud-based service (SaaS) .





Fusion, SNV, Indel, CNV, Expression & Immune Repertoire


Fusions
Variants
Indels
CNVs
Expression
Immune Repertoire



High-confidence variant calls

Comprehensive call statistics & annotations

  • Highlight your known variants of interest with targeted calling
  • Location-specific noise characterization based on cross-sample (cohort) analysis
  • Statistical power metrics to drive true positive & true negative calls
  • Annotations to identify variants of clear biological significance




Customize Quiver with your lab's data

User-annotated true and false positives

You can now add your own findings to your private installation of Analysis, in order to make sure fusions of known interest are highlighted, and avoid the distraction of known false positives





Validation sets

Create your own tests for automated validation of Analysis installation or upgrade

Samples with known mutational status can now be identified across your private instance of Analysis, and grouped together as a validation set. At any time, these sets can be re-run to ensure Analysis is performing exactly to your lab's requirements.





Sample-centric workflow

Jump straight to samples you need to review

Analysis now has a sample-centric interface that allows for direct access to all samples, instead of having to navigate through jobs first. A faster way to work through your case load!





Quiver fusion database integration

Detected fusion events are verified against the Archer Quiver Fusion Database so you know right away if your fusion is seen in the literature. Direct link-out to relevant publications.





Powerful run statistics and tiered result reporting

Analysis and quality metrics help determine the quality of the library sequenced and the success of the assay





Application Programming Interface (API)

Automate workflows by integrating Analysis with LIMS & other software

A RESTful API is now built in to automatically pull data from Archer Analysis. The API meets industry standards, including packaging data in JSON format, and is a powerful feature if you have downstream software for annotation, interpretation, and reporting processes.





Flexible configurations to suit your lab needs


Archer Analysis Unlimited Learn more about Analysis Unlimited

Private, cloud-based instance of Archer Analysis with scalable, pay-as-you-use compute resources

  • Set-it-and-forget-it: no hardware or maintenance
  • Process > 200 samples at a time
  • Pay only for what you use
Archer Analysis Virtual Machine Request a virtual machine

Archer Analysis packaged as a virtual machine for installation on your own hardware behind your firewall.

Archer FusionPlex
Archer VariantPlex
Archer Immunoverse
Archer Reveal ctDNA

How to contact us

Address

2477 55th Street, Suite 202

Boulder, CO 80301

Phone

Phone: (877) 771 1093

Phone: (303) 357 9001

All content © 2017 ArcherDX, Inc.

For Research Use Only. Not for use in diagnostic procedures. For Research Use Only. Not for use in diagnostic procedures.