What are the breakpoints of the expected fusions in the Archer SureShot ALK RET ROS1 Fusion Positive Control?

Please see the table below for the expected fusion breakpoint locations. Note that hg19 is used as the reference sequence.

Expected Fusion Position of 5' Breakpoint in RNA transcript Position of 3' Breakpoint in RNA transcript
EML4 exon 13 → ALK exon 20 chr2:42522656 chr2:29446394
CCDC6 exon 1 → RET exon 12 ch10:61665880 chr10:43612032
SLC34A2 exon 4 → ROS1 exon 32, and 34 chr4:25665952 chr6:117650602 (ROS1 exon 32) and chr6:117645578 (ROS1 exon 34)


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For Research Use Only. Not for use in diagnostic procedures. For Research Use Only. Not for use in diagnostic procedures.