Archer VariantPlex
Core Myeloid Kit

37 genes targeting critical AML, MPN and MDS markers

The VariantPlex Core Myeloid panel is a 37 gene targeted sequencing panel for critical AML, MPN and MDS markers. Powered by Anchored Multiplex PCR (AMP™) chemistry, the panel enables deep strand-specific amplification of molecular barcoded DNA fragments for Illumina® sequencing. After sequencing, Archer Analysis bioinformatics software deduplicates reads into unique starting molecules, correcting for sequencing and PCR-derived errors — enabling confident and sensitive mutation detection.

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For Research Use Only. Not for use in diagnostic procedures. For Research Use Only. Not for use in diagnostic procedures.


  • Confident, molecular barcode driven variant detection
  • Robust FLT3-ITD detection of all sizes and insertion points
  • Outstanding coverage, including challenging genes like CEBPA
  • Simple, lyophilized single day library preparation

Product Information

AB0101 - Variantplex® Core Myeloid Starter Kit, For Illumina® - 16 reactions

AB0100 - Variantplex® Core Myeloid Kit, For Illumina® - 8 reactions

AB0102 - Variantplex® Core Myeloid Kit, For Illumina® - 48 reactions

Illumina® Protocol Illumina® product insert
FAQs Archer Analysis
FLT3-ITD AMP tech note Get more info

Watch the video: FLT3-ITD detection with VariantPlex® Core Myeloid

The molecular landscape of leukemia and lymphoma has expanded exponentially in the last two decades, and the complexity and scope of biomarkers makes molecular analysis difficult for any single approach. The VariantPlex® Core Myeloid assay is powered by Anchored Multiplex PCR (AMP™) target enrichment chemistry to detect multiple mutation types and gene expression profiling in a single sample.


VariantPlex Core Myeloid Kit Features


Target genes


Total target size


Coverage uniformity > 20% mean


Input DNA required


Recommended # of reads



FFPE, bone marrow, blood, PBL

Sample type

Input recommendations for FFPE samples varies depending on Archer Preseq™ DNA QC score. 50ng input recommended in absence of PreSeq screening

Archer VariantPlex Core Myeloid Kit Targets


Need to modify a panel?

AMP chemistry is flexible and gene-level probe sets are modular. This means that any of our 94 wet lab-validated designs can be added to any preconfigured panel to build assays that fit your research goals. Archer Assay Designer gives you the power to easily determine assay content and keep current with the latest research.

Want to get more details on the VariantPlex Core Myeloid Kit?

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If you have any technical questions, please reach out to our expert Technical Support staff through or by calling ArcherDX directly at +1.303.357.9001.

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How to contact us


2477 55th Street, Suite 202

Boulder, CO 80301


Phone: (877) 771 1093

Phone: (303) 357 9001

All content © 2017 ArcherDX, Inc.

For Research Use Only. Not for use in diagnostic procedures. For Research Use Only. Not for use in diagnostic procedures.