The VariantPlex Core Myeloid panel is a 37 gene targeted sequencing panel for critical AML, MPN and MDS markers. Powered by Anchored Multiplex PCR (AMP™) chemistry, the panel enables deep strand-specific amplification of molecular barcoded DNA fragments for Illumina® sequencing. After sequencing, Archer Analysis bioinformatics software deduplicates reads into unique starting molecules, correcting for sequencing and PCR-derived errors — enabling confident and sensitive mutation detection.
For Research Use Only. Not for use in diagnostic procedures.
The molecular landscape of leukemia and lymphoma has expanded exponentially in the last two decades, and the complexity and scope of biomarkers makes molecular analysis difficult for any single approach. Archer Blood Cancer assays are powered by Anchored Multiplex PCR (AMP™) target enrichment chemistry to detect multiple mutation types and gene expression profiling in a single sample.
Total target size
Coverage uniformity > 20% mean
Input DNA required
Recommended # of reads
FFPE, bone marrow, blood, PBL
‡input recommendations for FFPE samples varies depending on Archer Preseq™ DNA QC score. 50ng input recommended in absence of PreSeq screening
AMP chemistry is flexible and gene-level probe sets are modular. This means that any of our 94 wet lab-validated designs can be added to any preconfigured panel to build assays that fit your research goals. Archer Assay Designer gives you the power to easily determine assay content and keep current with the latest research.
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