Archer VariantPlex
Core Myeloid Kit

37 genes targeting critical AML, MPN and MDS markers

The VariantPlex Core Myeloid panel is a 37 gene targeted sequencing panel for critical AML, MPN and MDS markers. Powered by Anchored Multiplex PCR (AMP™) chemistry, the panel enables deep strand-specific amplification of molecular barcoded DNA fragments for Illumina® sequencing. After sequencing, Archer Analysis bioinformatics software deduplicates reads into unique starting molecules, correcting for sequencing and PCR-derived errors — enabling confident and sensitive mutation detection.

For Research Use Only. Not for use in diagnostic procedures. For Research Use Only. Not for use in diagnostic procedures.


  • Confident, molecular barcode driven variant detection
  • Robust FLT3-ITD detection of all sizes and insertion points
  • Outstanding coverage, including challenging genes like CEBPA
  • Simple, lyophilized single day library preparation

Product Information

AB0101 - VariantPlex® Core Myeloid Starter Kit, for Illumina® - 16 reactions

AB0100 - VariantPlex® Core Myeloid Kit, for Illumina® - 8 reactions

AB0102 - VariantPlex® Core Myeloid Kit, for Illumina® - 48 reactions

Illumina® Protocol Illumina® product insert
FAQs Archer Analysis
FLT3-ITD AMP tech note Get more info

VariantPlex Core Myeloid Kit features


Target genes


Total target size


Coverage uniformity > 20% mean


Input DNA required


Recommended # of reads



FFPE, bone marrow, blood, PBL

Sample type

Input recommendations for FFPE samples varies depending on Archer Preseq™ DNA QC score. 50ng input recommended in absence of PreSeq screening

Archer VariantPlex Core Myeloid Kit targets


Don't see your gene?
Modify any panel with Archer Assay Designer.

VariantPlex Myeloid Kit capabilities

AMP-enabled FLT3-ITD detection

AMP-enabled FLT3-ITD detection

Independent and bidirectional probes are optimized to detect ITDs of all sizes.The reads originating from these probes are bioinformatically assembled by Archer Analysis to form longer consensus sequences that span the ITD. These longer sequences are then aligned to the reference genome to identify the presence of even very large ITDs.

High-complexity coverage across CEBPA

High-complexity coverage across CEBPA

Complete, strand-specific and bi-directional coverage of target exons, including traditionally difficult regions like CEBPA.

Robust CALR deletion detection

Robust CALR deletion detection

Powerful analysis of complex variants like CALR deletions can be detected using Archer Analysis due to the unique benefits of Anchored Multiplex PCR and extensive testing with positive samples and in-silico read generation technolog.

Request a quote or get more details

Fill out the form below and tell us about your scenario. A product manager will get in touch with you to answer your questions.

After submitting this form, you'll receive a confirmation email to let you know we've received your inquiry. An AcherDX representative will be in touch with you soon.

If you have any technical questions, please reach out to our expert Technical Support staff through or by calling ArcherDX directly at +1.303.357.9001.

Subscribe to stay in the loop

How to contact us


2477 55th Street, Suite 202

Boulder, CO 80301


Phone: (877) 771 1093

Phone: (303) 357 9001

All content © 2018 ArcherDX, Inc.

For Research Use Only. Not for use in diagnostic procedures. For Research Use Only. Not for use in diagnostic procedures.