The VariantPlex Core Myeloid panel is a 37 gene targeted sequencing panel for critical AML, MPN and MDS markers. Powered by Anchored Multiplex PCR (AMP™) chemistry, the panel enables deep strand-specific amplification of molecular barcoded DNA fragments for Illumina® sequencing. After sequencing, Archer Analysis bioinformatics software deduplicates reads into unique starting molecules, correcting for sequencing and PCR-derived errors — enabling confident and sensitive mutation detection.
For Research Use Only. Not for use in diagnostic procedures.
AB0101 - VariantPlex® Core Myeloid Starter Kit, for Illumina® - 16 reactions
AB0100 - VariantPlex® Core Myeloid Kit, for Illumina® - 8 reactions
AB0102 - VariantPlex® Core Myeloid Kit, for Illumina® - 48 reactions
Total target size
Coverage uniformity > 20% mean
Input DNA required†
Recommended # of reads
FFPE, bone marrow, blood, PBL
†Input recommendations for FFPE samples varies depending on Archer Preseq™ DNA QC score. 50ng input recommended in absence of PreSeq screening
Don't see your gene?
Modify any panel with Archer Assay Designer.
Independent and bidirectional probes are optimized to detect ITDs of all sizes.The reads originating from these probes are bioinformatically assembled by Archer Analysis to form longer consensus sequences that span the ITD. These longer sequences are then aligned to the reference genome to identify the presence of even very large ITDs.
Complete, strand-specific and bi-directional coverage of target exons, including traditionally difficult regions like CEBPA.
Powerful analysis of complex variants like CALR deletions can be detected using Archer Analysis due to the unique benefits of Anchored Multiplex PCR and extensive testing with positive samples and in-silico read generation technolog.
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