Archer VariantPlex
Myeloid Kit

75 genes targeting critical AML, MPN, MDS and lymphoid markers

The VariantPlex Myeloid panel is a 74-gene targeted sequencing panel for AML, MPN, MDS and some Lymphoid malignancy markers. Powered by Anchored Multiplex PCR (AMP™) chemistry, the panel enables deep strand-specific amplification of molecular barcoded DNA fragments for Illumina Sequencing. After sequencing, Archer Analysis deduplicates reads into unique starting molecules, correcting for sequencing and PCR-derived errors--enabling sensitive and confident mutation detection.

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For Research Use Only. Not for use in diagnostic procedures. For Research Use Only. Not for use in diagnostic procedures.


  • Confident and sensitive, unique molecule-driven variant detection
  • Robust FLT3-ITD detection of all sizes and insertion points
  • Outstanding coverage, including challenging genes like CEBPA
  • Simple, lyophilized single day library preparation
  • CNV detection for key genes in -7/7q, -5/5q, -13q, -11q, -12p/12p

Product Information

AB0109 - Variantplex® Myeloid Starter Kit, For Illumina® - 16 reactions

AB0108 - Variantplex® Myeloid Kit, For Illumina® - 8 reactions

Illumina® protocol
FAQs Archer Analysis
FLT3-ITD AMP tech note Get more info

Watch the video: FLT3-ITD detection with VariantPlex Myeloid

The molecular landscape of leukemia and lymphoma has expanded exponentially in the last two decades, and the complexity and scope of biomarkers makes molecular analysis difficult for any single approach. The Archer VariantPlex Myeloid assay is powered by Anchored Multiplex PCR (AMP™) target enrichment chemistry to detect multiple mutation types and gene expression profiling in a single sample.


VariantPlex Myeloid Kit Features


Gene targets


Total target size


Coverage uniformity > 20% mean


Input DNA required


Recommended # of reads



FFPE, bone marrow, blood, PBL

Sample type

Coverage uniformity and recommended number of reads expected.

input recommendations for FFPE samples varies depending on Archer Preseq™ DNA QC score. 50ng input recommended in absence of PreSeq screening

Archer VariantPlex Myeloid Kit Targets


Genes in red are expected targets for CNV detection.

* CNV detection only.

Need to modify a panel?

AMP chemistry is flexible and gene-level probe sets are modular. This means that any of our 94 wet lab-validated designs can be added to any preconfigured panel to build assays that fit your research goals. Archer Assay Designer gives you the power to easily determine assay content and keep current with the latest research.

Want to get more details on the VariantPlex Myeloid Kit?

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If you have any technical questions, please reach out to our expert Technical Support staff through or by calling ArcherDX directly at +1.303.357.9001.

How to contact us


2477 55th Street, Suite 202

Boulder, CO 80301


Phone: (877) 771 1093

Phone: (303) 357 9001

All content © 2017 ArcherDX, Inc.

For Research Use Only. Not for use in diagnostic procedures. For Research Use Only. Not for use in diagnostic procedures.