Acute Lymphoblastic Leukemia (ALL)



The Archer® FusionPlex Acute Lymphoblastic Leukemia (ALL) panel is a targeted next-generation sequencing (NGS) test to detect and identify fusions, point mutations and expression levels in 81 genes associated with Acute Lymphoblastic Leukemia, including all recurrent Ph-like ALL fusion events. The panel uses Archer’s proprietary Anchored Multiplex PCR (AMP™)-based enrichment to detect fusions of all target genes in a single sequencing test, even without prior knowledge of fusion partners or breakpoints.
Key Features
Comprehensive fusion detection

Covers all recurrent Ph-like ALL fusions.

Expression Profiling

Molecular barcodes enable relative expression level profiling in select genes.

Confirm fusion events

Expression imbalance confirmation for key fusions is detected using molecular barcodes.

Efficient, Lyophilized Workflow

Simultaneously interrogate hundreds of potential gene fusion events and relevant point mutations with under 2 million reads.

Sample versatility

Wide sample type compatibility, including FFPE.

Specifications and Performance

81

Gene Targets

> 10ng

Input Nucleic Acid Required*

> 95%

Unique Molecular On-Target %

2.5 hours

Hands-on Time

9 hours

Total Time

Illumina and
Ion Torrent

Platform

Blood, Fresh
Frozen, FFPE

Sample Types

*Input recommendations for FFPE samples vary depending on Archer PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening

Gene Targets

LEGEND

SNV/Indel
Expression
Fusion, splicing or exon-skipping

NeeD to Modify Your Panel?

Add any of our wet lab-validated designs to this panel with Archer Assay Designer to build an assay that fits your exact requirements.

  • Find Your Fit

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