Archer DX

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How to decipher noisy regions with per-variant sensitivity detection

Background noise isn’t static, so why should your sensitivity threshold be static? Traditional limit of detection measurements are based on static thresholds which average this noise, but Archer® scientists have recently developed a method to model the noise at each base position requiring only a small set of samples. This method allows for position-specific sensitivity thresholds, termed 95 MDAF, which increases confidence in variant detection in noisy regions.

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Validation of the Archer® FusionPlex® Sarcoma panel

A paper published in The Journal for Molecular Diagnostics shows a direct comparison between the Archer® FusionPlex® Sarcoma panel and conventional methods for gene fusion detection, including fluorescence in situ hybridization (FISH) and reverse transcriptase-PCR (RT-PCR)

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