Comprehensive Thyroid and Lung Panel

The Archer® Comprehensive Thyroid and Lung (CTL) panel is comprised of two complementary targeted targeted next-generation sequencing (NGS) panels to detect gene fusions, expression, SNVs, CNVs and indels from FFPE, fresh frozen or fine needle aspirate (FNA) samples. CTL is expertly designed to utilize both RNA and DNA in the FusionPlex® and VariantPlex® CTL panels in parallel to cover relevant exons in 45 genes implicated in lung and thyroid cancers.

What's Included

48 reactions of both FusionPlex and VariantPlex CTL panels

FusionPlex CTL + VariantPlex CTL panels AB0111

RNA Input

DNA Input

How It Works

Total nucleic acid (TNA) is purified from a formalin-fixed, paraffin-embedded (FFPE) sample or a fresh frozen tissue sample. As little as 10ng TNA is then used with each panel to generate a targeted library from RNA (FusionPlex Solid Tumor) and DNA (VariantPlex Solid Tumor).

The libraries are then pooled and sequenced, and the Archer Analysis bioinformatics platform analyzes the data to identify fusions and alternative splicing events from the RNA and copy number variants (CNVs), SNVs and indels from the DNA in the sample.

With the FusionPlex and VariantPlex parallel workflow, Archer provides the tools for in-house, comprehensive sample analysis for all relevant mutations, reducing necessary input amounts, costly send outs and long turn-around times.

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