Core Myeloid

The Archer® VariantPlex Core Myeloid panel is a 37 gene targeted sequencing panel for critical AML, MPN and MDS markers. Powered by Anchored Multiplex PCR (AMP™) chemistry, the panel enables deep strand-specific amplification of molecular barcoded DNA fragments for sequencing.
Key Features

Confident, molecular barcode driven variant detection.


Robust FLT3-ITD detection of all sizes and insertion points.


Complete coverage, including challenging genes like CEBPA.


Simple, lyophilized single day library preparation.

Specifications and Performance


Gene Targets


Total Target Size

≥ 10ng

Input DNA Required‡

> 99.8%

Coverage Uniformity > 20% Mean

2.5 hours

Hands-On Time

1 Day

Total Time



Blood, Bone Marrow, PBL, FFPE

Sample Types

†Expected coverage uniformity at the recommended read depth.
‡input recommendations for FFPE samples vary depending on Archer® PreSeq® DNA QC score. 50ng input recommended in absence of PreSeq® screening

Gene Targets


Internal tandem duplication (ITD)

Note: Fusions involving BCR and TCR loci, including IGH, IGL and IGK, are targeted for expression and may not be explicitly called as a fusion because these often do not result in chimeric transcripts.

NeeD to Modify Your Panel?

Add any of our wet lab-validated designs to this panel with Archer Assay Designer to build an assay that fits your exact requirements.

  • Find Your Fit

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