The Archer® Comprehensive Solid Tumor Kit is comprised of two complementary targeted NGS kits to detect gene fusions, expression, SNVs, CNVs and indels from FFPE or fresh frozen samples. CST is expertly designed to utilize both DNA and RNA in VariantPlex® and FusionPlex® Solid Tumor kits in parallel to cover relevant exons in 113 genes associated with solid tumors.
48 reactions of both FusionPlex and VariantPlex Solid Tumor kits
FOR RESEARCH USE ONLY. Not for use in diagnostic procedures.
Total nucleic acid (TNA) is purified from a formalin-fixed, paraffin-embedded (FFPE) sample or a fresh frozen tissue sample. As little as 10ng TNA is then used with each kit to generate a targeted library from RNA (FusionPlex Solid Tumor) and DNA (VariantPlex Solid Tumor).
The libraries are then pooled and sequenced, and the Archer Analysis bioinformatics platform analyzes the data to identify fusions and alternative splicing events from the RNA and copy number variants (CNVs), SNVs and indels from the DNA in the sample.
With the FusionPlex and VariantPlex parallel workflow, Archer provides the tools for in-house, comprehensive sample analysis for all relevant mutations, reducing necessary input amounts, costly send outs and long turn-around times.
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