The Archer® Comprehensive Thyroid and Lung (CTL) Kit is comprised of two complementary targeted NGS panels to detect gene fusions, expression, SNVs, CNVs and indels from FFPE, fresh frozen or fine needle aspirate (FNA) samples. CTL is expertly designed to utilize both DNA and RNA in the VariantPlex® and FusionPlex® CTL panels in parallel to cover relevant exons in 45 genes implicated in lung and thyroid cancers.
48 reactions of both FusionPlex and VariantPlex CTL kits
FOR RESEARCH USE ONLY. Not for use in diagnostic procedures.
Total nucleic acid (TNA) is purified from a formalin-fixed, paraffin-embedded (FFPE) sample or a fine-needle aspirate (FNA). As little as 10ng TNA is then used with each panel to generate a targeted library from RNA (FusionPlex CTL) and DNA (VariantPlex CTL).
The libraries are then pooled and sequenced, and the Archer Analysis bioinformatics platform analyzes the data to identify fusions, single nucleotide variants (SNVs) and insertions/deletions (indels) from the RNA and copy number variations (CNVs), SNVs and indels from the DNA in the sample.
With the FusionPlex and VariantPlex parallel workflow, Archer provides the tools for in-house, comprehensive sample analysis for all relevant mutations, reducing necessary input amounts, costly send outs and long turn-around times.
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