Archer Custom NGS Assays
Custom NGS Assays

The ultimate mix-and-match sequencing technology


Create from scratch or modify an existing panel without sacrificing performance.

Rapidly design your own next-generation sequencing assay for DNA, RNA or ctDNA using Archer® Assay Designer. Whether you design an assay from scratch using your own list of genes and gene features or modify an existing Archer catalog or Focus panel, Assay Designer is your web-based portal to ultimate panel build flexibility.

Build your custom assay now Learn more about Focus kits

Scalable and flexible NGS implementation

Have questions about your particular scenario? Request a consultation with an Archer expert

Videos about building custom NGS assays with Archer

 
 


Archer Assay Designer capabilities

Expert primer design
High on-target percentage and primer uniformity with Archer assays

Primer design is the foundation of next-generation sequencing (NGS)-based assay performance, and our in-house design experts leverage the design flexibility of AMP chemistry to ensure that all primers generated in Assay Designer deliver high uniformity and low off-targeting.

Simple & intuitive

Assay Designer has a simple, intuitive interface to help you quickly build the target panel that you want. Browse through hundreds of wet lab-tested and verified designs, or use state-of-the-art primer design tools to build the assay to fit your needs.

Top-notch performance
Target design rate for 4 modular panel designs ranging from 12 to 914 targets.

Assay Designer boasts cutting-edge primer design software and an expansive internal knowledge base of target designs and validated primer sets. Designed with maximum flexibility and unparalleled performance in mind, you can be assured that your targets will achieve maximum coverage.


Get started today with high-performance customized NGS assays.

Anchored Multiplex PCR enrichment chemistry is flexible and the primer sets are modular, meaning new targets can be added to an existing Archer Assay without impacting panel performance. Whether you design an assay from scratch or select from hundreds of pre-designed and tested gene panels, you'll have the utmost confidence and flexibility in your custom panel.

The devil is in the details

After target selection, quickly review and modify any target details before submitting the design.


Expert design review

When Assay Designer completes your design you will be provided with a full design report. Proceed by requesting a review by our in-house Assay Development Team.


Ordering your custom assay

Once you submit a purchase order for your design, you will receive your assay in approximately 4-5 weeks. Your custom panel will come with all of the lyophilized reagents needed for library preparation along with access to Archer Analysis.

Build your custom assay now


Need a place to start? Save some time with an Archer Focus kit.

What's your focus?

All Archer panels are easily modified; however, Archer Focus panels make great building-blocks for your custom assay. They are small, disease-specific panels of pre-validated targets that are made to order. Each can be used as a starting point in Assay Designer to accomodate your needs.

Focus Panels are great starting points for building customized kits

VariantPlex
TP53 assay

1 gene

TP53

Illumina®
 

100K recommended read depth

Highlights

  • Superior TP53 coverage
  • Optimized for full exon coverage with a low number of sequencing reads

VariantPlex
BRCA v2

2 genes

BRCA1, BRCA2

Illumina®
 

500K recommended read depth

Highlights

  • Deep coverage over all coding regions
  • Confident de novo variant detection
Performance

VariantPlex
BRCA and PALB2 Focus

3 genes

BRCA1, BRCA2, PALB2

Illumina®
 

500K recommended read depth

Highlights

  • Rapid, lyophilized workflow
  • Complete coding region coverage
Performance

FusionPlex
Lung Focus

5 genes

ALK, RET, ROS1, NTRK1, MET

Illumina®
Ion Torrent

500K recommended read depth

Highlights

  • Highly focused detection of oncogenic fusions in lung cancer
  • Includes select insertions and point mutations in ALK and RET, including known resistant point mutations
  • Captures MET exon 14 skipping events

FusionPlex
Brain Focus

10 genes

BRAF, EGFR, EWSR1, FGFR3, MYB, NTRK1, NTRK2, NTRK3, PDGFB, PDGFRA

Illumina®
Ion Torrent

500K recommended read depth

Highlights

  • RNA fusion detection for common brain tumor translocations
  • Allows for initial sample stratification across pediatric and adult brain tumor samples resulting from fusion events
  • Captures prominent BRAF, EGFR and PDGFRA mutations

FusionPlex
Myeloid Focus

9 genes

RUNX1, RARA, NUP214, NUP98, CBFB, ABL1, BCR, RBM15, KMT2A

Illumina®
Ion Torrent

500K recommended read depth

Highlights

  • Coverage of critical myeloid fusion targets, including ABL1 resistant point mutations
  • High degree of multiplexing (1M reads)
  • Novel fusion detection

VariantPlex
AML Focus

11 genes

ASXL1, CEBPA, DNMT3A, FLT3, IDH1, IDH2, JAK2, KIT, NPM1, RUNX1, TP53

Illumina®

750K recommended read depth

Highlights

  • Robust FLT3-ITD detection
  • Deep, full coverage of CEBPA

Reveal ctDNA
Lung Focus

12 genes

Hotspots in:
ALK, AKT1, BRAF, CTNNB1, EGFR, ERRB2, KRAS, MAP2K1, MET, NRAS, PIK3CA, ROS1

Illumina®

1M recommended read depth

Highlights

  • Simple, lyophilized workflow
  • MBC-enabled error correction and low-allele fraction (AF) detection

VariantPlex
Solid Tumor Focus

20 genes

AKT1, BRAF, EGFR, ERBB2, FOXL2, GNA11, GNAQ, GNAS, HRAS, IDH1, IDH2, KIT, KRAS, MET, NRAS, PDGFRA, PIK3CA, RET, TERTp, TP53

Illumina®

750K recommended read depth

Highlights

  • Built for challenging FFPE samples
  • MBC-powered variant detection

Get a quote

How to contact us

Address

2477 55th Street, Suite 202

Boulder, CO 80301

Phone

Phone: (877) 771 1093

Phone: (303) 357 9001

All content © 2018 ArcherDX, Inc.

For Research Use Only. Not for use in diagnostic procedures. For Research Use Only. Not for use in diagnostic procedures.