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Quiver® Fusion Database

Looking for published gene fusions? Curious if your detected fusion is really novel?

The Archer® Quiver® database is a database of 9,368 published gene fusion partners and 10,869 unique breakpoints derived from 3,006 peer-reviewed publications. Archer® Quiver® collates information from 6 publicly available information sources:

Search by individual genes or gene fusions

Archer® Quiver® can distinguish synonymous gene names in the literature, reporting on the canonical name.

Search for published data on particular gene fusions

Find Archer® FusionPlex® assays targeting your gene or fusion of interest.

Shows disease states associated with particular gene fusions in the literature

Links to existing gene-specific resources, like PubMed, OMIM, NCBI, UCSC

Database Metrics

Current database version 3.10
Genes Included 7,156
Unique Fusion Partners 9,368
Unique Breakpoints 10,869
Publications Cited 3,006

References

  1. Sanger Institute Catalogue Of Somatic Mutations In Cancer web site, http://www.sanger.ac.uk/cosmic Bamford et al (2004) The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br J Cancer, 91,355-358.
  2. Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer (2014). Mitelman F, Johansson B and Mertens F (Eds.)
  3. ChimerDB 2.0-a knowledgebase for fusion genes updated” Nucleic Acids Res. 38(Database issue), D81-85. (2010 Jan)
  4. dbCRID: a database of chromosomal rearrangements in human diseases. Nucleic Acids Res. 2011 Jan;39(Database issue):D895-900. doi: 10.1093/nar/gkq1038
  5. TICdb: a collection of gene-mapped translocation breakpoints in cancer, BMC Genomics 2007, 8:33 doi:10.1186/1471-2164-8-33
  6. ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data. Nucleic Acids Research 41 (D1): D142-D151. doi:10.1093/nar/gks1041

Limitations of Use

This product was developed, manufactured, and sold for in vitro use only. The product is not suitable for administration to humans or animals. MSDS sheets relevant to this product are available upon request.

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