FusionPlex ALL

Acute Lymphoblastic Leukemia (ALL)

The FusionPlex Acute Lymphoblastic Leukemia (ALL) panel is a targeted next-generation sequencing (NGS) product to detect and identify fusions, point mutations and expression levels in 81 genes associated with ALL, including all recurrent Ph-like ALL fusion events. The panel uses Anchored Multiplex PCR (AMP™)-based enrichment to detect fusions of all target genes in a single sequencing product, even without prior knowledge of fusion partners or breakpoints.

Thank You

Comprehensive Fusion Detection

AMP chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the fusion partner is known.

Splice Variants

Detect cancer-associated isoforms and alternative splicing events.

Low Input

Purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.

Simple, Lyophilized Workflow

Easy-to-handle lyophilized reagents and a simple workflow to minimize errors and reduce turn-around time.

Properties

Specifications

Gene Targets

81

Input Nucleic Acid Required*

≤10ng

Unique Molecular On-Target %

>95%

Hands-On Time

2.5 Hour

Total Time

9 Hours

Platform

Illumina® and Ion Torrent®

Sample Types

Blood, Fresh frozen and FFPE

Input recommendations for FFPE samples vary depending on PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening

LEGEND

SNV/Indel
Fusion, splicing or exon-skipping
Expression

Product Information

Illumina®

Ion Torrent™

Archer® Analysis

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Customize this panel by adding any of our functionally-tested designs. Assay Marketplace lets you browse our catalog of targeted AMP chemistry-based panels, modify an existing panel with additional targets, or create a new panel that fits your exact requirements.

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For Research Use Only. Not for use in diagnostic procedures.

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For Research Use Only. Not for use in diagnostic procedures.