The VariantPlex Core Myeloid panel is next-generation targeted sequencing (NGS) product for acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS) and some lymphoid malignancy markers. Powered by Anchored Multiplex PCR (AMP™) chemistry, the panel enables deep strand-specific amplification of molecular barcoded DNA fragments for sequencing.
Complex Variant Detection
Coverage combined with powerful bioinformatics enable variant detection in traditionally difficult regions like CEBPA & FLT3.
AMP chemistry was purpose-built for wide sample compatibility, including low-input and degraded samples such as FFPE tissue.
Quantitative CNV Detection
Molecular barcoded fragments counting provides robust copy number analysis.
Simple, Lyophilized Workflow
Easy-to-handle lyophilized reagents and a simple workflow to minimize errors and reduce turn-around time.
Input DNA Required*
Coverage Uniformity >20% Mean+
Blood, Bone Marrow, PBL and FFPE
+Expected coverage uniformity at the recommended read depth. *Input recommendations for FFPE samples vary depending on PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening