Custom Panels

Custom Panels

The NGS panel you really want

Design your own panel with genes of interest for targeted next-generation sequencing (NGS) using RNA, DNA or ctDNA. 

ArcherDX offers two options for custom panel creation: Archer® Assay Designer and Designer Pro.

Key Features

Expert Primer Design

Primer design is the foundation of NGS-based panel performance, and our in-house design experts leverage the design flexibility of Anchored Multiplex PCR (AMP™) chemistry to ensure that all primers generated in Assay Designer deliver high uniformity and low off-targeting.

Simple and Intuitive

Assay Designer has a simple, intuitive interface to help you quickly build the target panel that you want. Browse through hundreds of wet lab-tested and verified designs or use state-of-the-art primer design tools to build the panel to fit your needs.

Exceptional Performance

Assay Designer boasts cutting-edge primer design software and an expansive internal knowledge base of target designs and validated primer sets. Designed with maximum flexibility and unparalleled performance in mind, you can be assured that your targets will achieve complete coverage.

Full Support

With Designer Pro, your panel is iteratively designed and functionally validated on a range of sample types and qualities. From research to data reviews, panel configuration, training and post launch support, we’ve got you covered.

Build your custom panel

Assay Designer – Get started with your panel today

Archer® Assay Designer is an online tool that allows the customer to design new biomarker targets, mix and match existing targets or add new targets to an existing product. Most panels can be created within Assay Designer — an online design tool for users to build customized RNA, DNA or ctDNA research panels using functionally validated or newly designed primers quickly and economically.

Designer Pro – Archer’s Premium Customization Service

For customers seeking an additional layer of validation, there’s Designer Pro. Our expert scientists design, wet lab-validate and optimize the panel to your specifications. Extensive testing, data sharing and reports for signoff during development of your panel ensure optimal performance on your sample type before you receive your panels. Archer also provides full hands-on training and bioinformatic support for a quick and easy transition into your lab.

NEED A PLACE TO START?
Save some time with an ArcherDX Focus Panel

What’s your focus?
All Archer panels are easily modified, however, Archer Focus panels make great building-blocks for your custom panel. They are small, disease-specific panels of pre-validated targets that are made to order. Each can be used as a starting point in Assay Designer to accommodate your needs.

Focus panels are great starting points for building customized panels.

VariantPlex® TP53 Panel
1 Gene
  • TP53
Illumina®
  • 100K Recommended Read Depth
Highlights
  • Maximum TP53 Coverage
  • Optimized for full exon coverage with a low number of sequencing reads
VariantPlex BRCA V2
2 Gene
  • BRCA1, BRCA2
Illumina
  • 500K Recommended Read Depth
Highlights
  • Deep coverage over all coding regions
  • Confident de novo variant detection
VariantPlex BRCA and PALB2 Focus
3 Gene
  • BRCA1, BRCA2, PALB2
Illumina
  • 500K Recommended Read Depth
Highlights
  • Rapid, lyophilized workflow
  • Complete coding region coverage
VariantPlex AML Focus
11 Gene
  • ASXL1, CEBPA, DNMT3A, FLT3, IDH1, IDH2, JAK2, KIT, NPM1, RUNX1, TP53
Illumina
  • 750K Recommended Read Depth
Highlights
  • Robust FLT3-ITD detection
  • Deep, full coverage of CEBPA
VariantPlex Solid Tumor Focus
20 Gene
  • AKT1, BRAF, EGFR, ERBB2, POXL2, GNA11, GNAQ, GNAS, HRAS, IDH1, IDH2, KIT, KRAS, MET, NRAS, PDGFRA, PIK3CA, RET, TERTp, TP53
Illumina
  • 750K Recommended Read Depth
Highlights
  • Built for challenging FFPE samples
  • MBC-powered variant detection
FusionPlex® Lung Focus
5 Gene
  • ALK, RET, ROS1, NTRK1, MET
Illumina and Ion Torrent™
  • 500K Recommended Read Depth
Highlights
  • Highly focused detection of oncogenic fusions in lung cancer
  • Includes select insertions and point mutations in ALK and RET, including known resistant point mutations
  • Captures MET exon 14 skipping events
FusionPlex Brain Focus
10 Gene
  • BRAF, EGFR, EWSR1, FGFGR3, MYB, NTRK1, NTRK2, NTRK3, PDGFB, PDGFRA
Illumina and Ion Torrent
  • 500K Recommended Read Depth
Highlights
  • RNA fusion detection for common brain tumor translocations
  • Allows for initial sample stratification across pediatric and adult brain tumor samples resulting from fusion events
  • Captures prominent BRAF, EGFR and PDGFRA mutations
FusionPlex Myeloid Focus
9 Gene
  • RUNX1, RARA, NUP214, NUP98, CBFB, ABL1, BCR, RBM15, KMT2A
Illumina and Ion Torrent
  • 500K Recommended Read Depth
Highlights
  • Coverage of critical myeloid fusion targets, including ABL1 resistant point mutations
  • High degree of multiplexing (1M reads)
  • Novel fusion detection
LiquidPlex Lung Focus
12 Genes
  • RUNX1, RARA, NUP214, NUP98, CBFB, ABL1, BCR, RBM15, KMT2A
Illumina
  • 1M Recommended Read Depth
Highlights
  • Simple, lyophilized workflow
  • MBC-enabled error correction and low-allele fraction (AF) detection

Ready to Start?
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For Research Use Only. Not for use in diagnostic procedures.