FusionPlex Core Solid Tumor

Core Solid Tumor

The FusionPlex Core Solid Tumor panel is a targeted next-generation sequencing (NGS) research product that expands on our well-adopted FusionPlex product portfolio to further drive discovery.

Archer’s FusionPlex Core Solid Tumor panel enables simultaneous detection of fusions, splice variants, key SNV/Indels, and relative RNA expression from the same input to drive cost efficiency. The panel features expanded SNV/Indel coverage over key genes, including tumor suppressors. With Anchored Multiplex PCR (AMP™) chemistry at the core and an integrated bioinformatic platform, FusionPlex targeted NGS assays offer streamlined RNA-based analysis from sample to data.

  • Key Features
  • Specifications
  • Gene Targets
  • Additional Resources
Comprehensive Fusion Detection

Comprehensive Fusion Detection
AMP chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the fusion partner is known.

Splice Variants

Identify relevant isoforms and alternative splicing events.

SNV & Indel Detection from the Same Input

Purpose built for the simultaneous detection of multiple mutation types from the same limited input.

Properties

Specifications

Gene Targets
57
Input Nucleic Acid Required*
≤10ng
Sample Types
FFPE, Fresh Frozen, FNA, Cytology Specimens
Hands-On Time
3.5 hours
Total Time
1.5 days
Platform
Illumina® and Ion Torrent™

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200ng is recommended.

Product Information
Illumina®
Ion Torrent™
Archer® Analysis

AKT1

ALK

AXL

BRAF

BRD3

BRD4

CTNNB1

CYSLTR2

DDR

DNAJB1

EGFR

ERBB2

ERBB4

ERG

ESR1

FGFR1

FGFR2

FGFR3

GNA11

GNAQ

GNAS

H3F3A

HIST1H3B

HRAS

IDH1

IDH2

KEAP1

KIT

KRAS

LTK

MAP2K1

MAP3K3

MAP3K8

MET

MYB

MYBL1

NRAS

NRG1

NTRK1

NTRK2

NTRK3

NUTM1

PAX8

PDGFRA

PIK3CA

POLD1

POLE

PPARG

PRKCA

PRKCB

RAF1

RET

ROS1

STK11

TMPRSS2

TP53

TRIM11

LEGEND

SNV/Indel
Fusion, splicing or exon-skipping

The FusionPlex Lung v2 panel Assay Marketplace
Customize this panel by adding any of our functionally-tested designs. Assay Marketplace lets you browse our catalog of targeted AMP chemistry-based panels, modify an existing panel with additional targets, or create a new panel that fits your exact requirements.

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For Research Use Only. Not for use in diagnostic procedures.

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For Research Use Only. Not for use in diagnostic procedures.