Lung

The Archer® FusionPlex Lung panel is a targeted next-generation sequencing (NGS) product to detect EGFR vIII and MET exon 14 skipping events along with prominent ALK, BRAF, FGFR, NRG1, NTRK, RET, and ROS1 fusions and select point mutations in 14 key gene targets associated with lung cancer. The panel is powered by Archer’s proprietary Anchored Multiplex PCR (AMP™)  target enrichment chemistry to detect fusions in a single sequencing product, even without prior knowledge of fusion partners or breakpoints.

  • Key Features
  • Specifications
  • Gene Targets
  • Additional Resources
Comprehensive Fusion Detection

AMP chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the fusion partner is known.

Splice Variants

Detect cancer-associated isoforms and alternative splicing events.

Low Input

Purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.

Simple, Lyophilized Workflow

Easy-to-handle lyophilized reagents and a simple workflow to minimize errors and reduce turn-around time.

Properties

Specifications

Gene Targets
14
Input Nucleic Acid Required*
≤10ng
Unique Molecular On-Target %
>97%
Sample Types
Fresh frozen and FFPE
Hands-On Time
2.5 hours
Total Time
9 Hours
Platform
Illumina® and Ion Torrent™

Input recommendations for FFPE samples vary depending on Archer PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening

ALK

BRAF

EGFR

FGFR1

FGFR2

FGFR3

KRAS

MET

NRG1

NTRK1

NTRK2

NTRK3

RET

ROS1

LEGEND

SNV/Indel
Fusion, splicing or exon-skipping

Product Information
Illumina
  • AB0121 - 8-reactions
  • AB0129 - 48-reactions
  • AB0031 - 16-reactions – Ask about our starter panel​
Archer Analysis

Need to modify your panel?

Add any of our wet lab-validated designs to this panel with Archer Assay Designer to build an assay that fits your exact requirements.

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For Research Use Only. Not for use in diagnostic procedures.