Oncology Research

The Archer® FusionPlex Oncology Research panel is a targeted next-generation sequencing (NGS) product to simultaneously detect and identify fusions and other mutations associated with 75 genes found in ribonucleic acid (RNA) transcripts that are linked to various cancers. This panel is extensive and purpose-built to advance fusion discovery, including research efforts in the area of Ph-like acute lymphoblastic leukemia (ALL) fusions.

  • Key Features
  • Specifications
  • Gene Targets
  • Additional Resources
Comprehensive Fusion Detection

AMP chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the fusion partner is known.

Splice Variants

Detect cancer-associated isoforms and alternative splicing events.

Low Input

Purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.

Simple, Lyophilized Workflow

Easy-to-handle lyophilized reagents and a simple workflow to minimize errors and reduce turn-around time.

Properties

Specifications

Gene Targets
75
Input Nucleic Acid Required*
≤10ng
Unique Molecular On-Target%
>96%
Hands-on Time
2.5 hours
Total Time
9 Hour
Platform
Illumina® and Ion Torrent™
Sample Types
Fresh frozen and FFPE

Input recommendations for FFPE samples vary depending on Archer PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening

ABL1

ABL2

AKT1

AKT2

AKT3

ALK

ARHGAP26

AXL

BRAF

BRD3

BRD4

CRLF2

CSF1R

EGFR

EPOR

ERBB2

ERBB4

ERG

ESR1

ESRRA

ETV1

ETV4

ETV5

ETV6

EWSR1

FGFR1

FGFR2

FGFR3

FGR

IL2RB

INSR

JAK1

JAK2

JAK3

KIT

MAML2

MAST1

MAST2

MET

MSMB

MUSK

MYB

MYC

NOTCH1

NOTCH2

NRG1

NTRK1

NTRK2

NTRK3

NUMBL

NUT

PDGFRA

PDGFRB

PIK3CA

PKN1

PPARG

PRKCA

PRKCB

PTK2B

RAF1

RARA

RELA

RET

ROS1

RSPO2

RSPO3

SYK

TERT

TFE3

TFEB

THADA

TMPRSS2

TSLP

TYK2

LEGEND

SNV/Indel
Fusion, splicing or exon-skipping

Product Information
ILLUMINA®
  • AB0009 - 8-reactions
  • AB0061 - 48-reactions
  • AB0031 - 16-reactions – Ask about our starter panel​​
ION TORRENT™
  • AB0010 - 8-reactions
  • AB0062 - 48-reactions
  • AB0028 - 16-reactions – Ask about our starter panel​​
Archer® Analysis

Need to modify your panel?

Add any of our wet lab-validated designs to this panel with Archer Assay Designer to build an assay that fits your exact requirements.

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For Research Use Only. Not for use in diagnostic procedures.