Oncology Research
The Archer® FusionPlex Oncology Research panel is a targeted next-generation sequencing (NGS) product to simultaneously detect and identify fusions and other mutations associated with 75 genes found in ribonucleic acid (RNA) transcripts that are linked to various cancers. This panel is extensive and purpose-built to advance fusion discovery, including research efforts in the area of Ph-like acute lymphoblastic leukemia (ALL) fusions.
- Key Features
- Specifications
- Gene Targets
- Additional Resources
Comprehensive Fusion Detection
AMP chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the fusion partner is known.
Splice Variants
Detect cancer-associated isoforms and alternative splicing events.
Low Input
Purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.
Simple, Lyophilized Workflow
Easy-to-handle lyophilized reagents and a simple workflow to minimize errors and reduce turn-around time.
Properties
Specifications
Gene Targets
75
Input Nucleic Acid Required*
≤10ng
Unique Molecular On-Target%
>96%
Hands-on Time
2.5 hours
Total Time
9 Hour
Platform
Illumina® and Ion Torrent™
Sample Types
Fresh frozen and FFPE
Input recommendations for FFPE samples vary depending on Archer PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening
ABL1
ABL2
AKT1
AKT2
AKT3
ALK
ARHGAP26
AXL
BRAF
BRD3
BRD4
CRLF2
CSF1R
EGFR
EPOR
ERBB2
ERBB4
ERG
ESR1
ESRRA
ETV1
ETV4
ETV5
ETV6
EWSR1
FGFR1
FGFR2
FGFR3
FGR
IL2RB
INSR
JAK1
JAK2
JAK3
KIT
MAML2
MAST1
MAST2
MET
MSMB
MUSK
MYB
MYC
NOTCH1
NOTCH2
NRG1
NTRK1
NTRK2
NTRK3
NUMBL
NUT
PDGFRA
PDGFRB
PIK3CA
PKN1
PPARG
PRKCA
PRKCB
PTK2B
RAF1
RARA
RELA
RET
ROS1
RSPO2
RSPO3
SYK
TERT
TFE3
TFEB
THADA
TMPRSS2
TSLP
TYK2
LEGEND
SNV/Indel
Fusion, splicing or exon-skipping
Product Information
ILLUMINA®
- AB0009 - 8-reactions
- AB0061 - 48-reactions
- AB0031 - 16-reactions – Ask about our starter panel
ION TORRENT™
- AB0010 - 8-reactions
- AB0062 - 48-reactions
- AB0028 - 16-reactions – Ask about our starter panel
Archer® Analysis
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