FusionPlex Sarcoma V2

Sarcoma v2

The FusionPlex Sarcoma v2 panel is a targeted next-generation sequencing (NGS) research product that expands on our FusionPlex Sarcoma panel. The updated design covers key fusions and variants in 63 genes relevant in sarcomas. FusionPlex uses RNA instead of DNA as input material, which allows for more accurate and more cost-effective fusion detection than DNA-based hybrid capture techniques. FusionPlex places gene-specific primers near known fusion breakpoints to identify RNA abnormalities with a single primer. Because FusionPlex can identify known and novel alterations with a limited number of primers, it can detect fusions more efficiently and accurately than DNA-based approaches

  • Key Features
  • Specifications
  • Gene Targets
  • Additional Resources
Comprehensive Fusion Detection

AMP chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the fusion partner is known.

Quiver® Fusion Database

Powerful fusion analysis combined with a curated database of relevant known translocations.

Low Input

Purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.

Simple, Lyophilized Workflow

Easy-to-handle lyophilized reagents and a simple workflow to minimize errors and reduce turnaround time.

Properties

Specifications

Gene Targets
63
Input Nucleic Acid Required*
≤10ng
Unique Molecular On-Target %
>95%
Hands-On Time
3.5 Hours
Total Time
1.5 days
Platform
Illumina® and Ion Torrent™
Sample Types
Fresh frozen and FFPE

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200ng is recommended.

Product Information
Illumina
ION TORRENT™

Need to modify your panel?

Add any of our wet lab-validated designs to this panel with Archer Assay Designer to build an assay that fits your exact requirements.

ALK

BCOR

BRAF

CAMTA1

CCNB3

CIC

CSF1

CTNNB1

EGFR

EPC1

ERG

ESR1

ETV1

ETV4

ETV5

ETV6

EWSR1

FGFR1

FGFR2

FGFR3

FOS

FOSB

FOXO1

FUS

GLI1

HMGA2

JAZF1

MBTD1

MDM2

MEAF6

MET

MGEA5

MKL2

MYOD1

NCOA1

NCOA2

NCOA3

NR4A3

NTRK1

NTRK2

NTRK3

NUTM1

PAX3

PDGFB

PDGFRA

PHF1

PLAG1

PRKCA

PRKCB

PRKCD

RAF1

RET

ROS1

SS18

STAT6

TAF15

TCF12

TFE3

TFG

USP6

VGLL2

YAP1

YWHAE

LEGEND

SNV/Indel
Fusion, splicing or exon-skipping

Need to modify your panel?

Add any of our wet lab-validated designs to this panel with Archer Assay Designer to build an assay that fits your exact requirements.

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For Research Use Only. Not for use in diagnostic procedures.

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For Research Use Only. Not for use in diagnostic procedures.