Solid Tumor

The Archer® FusionPlex Solid Tumor panel is a targeted next-generation sequencing (NGS) product to simultaneously detect and identify fusions and other mutations associated with over 50 genes linked to various carcinomas. This panel uses Archer’s proprietary Anchored Multiplex PCR (AMP™)-based enrichment to detect all fusions associated with the genes in a single sequencing product, even without prior knowledge of fusion partners or breakpoints.

  • Key Features
  • Specifications
  • Gene Targets
  • Additional Resources
Comprehensive Fusion Detection

AMP chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the fusion partner is known.

Splice Variants

Detect cancer-associated isoforms and alternative splicing events.

Low Input

Purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.

Customization

Create from scratch or modify any panel to keep up with the pace of discovery.

Properties

Specifications

Gene Targets
53
Input Nucleic Acid Required*
≤10ng
Unique Molecular On-Target%
>92%
Hands-on Time
2.5 hours
Total Time
9 hours
Platform
Illumina® and Ion Torrent™
Sample Types
Fresh frozen and FFPE

Input recommendations for FFPE samples vary depending on Archer PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening

AKT3

ALK

ARHGAP26

AXL

BRAF

BRD3

BRD4

EGFR

ERG

ESR1

ETV1

ETV4

ETV5

ETV6

EWSR1

FGFR1

FGFR2

FGFR3

FGR

INSR

MAML2

MAST1

MAST2

MET

MSMB

MUSK

MYB

NOTCH1

NOTCH2

NRG1

NTRK1

NTRK2

NTRK3

NUMBL

NUTM1

PDGFRA

PDGFRB

PIK3CA

PKN1

PPARG

PRKCA

PRKCB

RAF1

RELA

RET

ROS1

RSPO2

RSPO3

TERT

TFE3

TFEB

THADA

TMPRSS2

LEGEND

SNV/Indel
Fusion, splicing or exon-skipping

Product Information
ILLUMINA®
  • AB0005 - 8-reactions
  • AB0061 - 48-reactions
ION TORRENT™
  • AB0006 - 8-reactions
  • AB0058 - 48-reactions
Archer® Analysis

Need to modify your panel?

Add any of our wet lab-validated designs to this panel with Archer Assay Designer to build an assay that fits your exact requirements.

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For Research Use Only. Not for use in diagnostic procedures.