FusionPlex Solid Tumor V2

Pan Solid Tumor v2

The FusionPlex Pan Solid Tumor v2 panel is a targeted next-generation sequencing (NGS) research product that expands on the FusionPlex Solid Tumor panel to include key fusions and variants relevant across solid tumors and sarcomas in 137 genes. Representing our most comprehensive fusion coverage, the updated design includes key fusions and variants. This panel uses Anchored Multiplex PCR (AMP™)-based enrichment to detect all fusions associated with the genes in a single sequencing product, even without prior knowledge of fusion partners or breakpoints.

  • Key Features
  • Specifications
  • Gene Targets
  • Additional Resources
Comprehensive Fusion Detection

AMP chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the fusion partner is known.

Splice Variants

Detect cancer-associated isoforms and alternative splicing events.

Low Input

Purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.

Customization

Create from scratch or modify any panel to keep up with the pace of discovery.

Properties

Specifications

Gene Targets
137
Input Nucleic Acid Required*
≤10ng
Unique Molecular On-Target%
>96%
Hands-on Time
3.5 hours
Total Time
1.5 days
Platform
Illumina® and Ion Torrent™
Sample Types
Fresh frozen and FFPE

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200ng is recommended.

Product Information
ILLUMINA®
ION TORRENT™
Archer® Analysis

ACVR2A

AKT1

AKT2

AKT3

ALK

AR

ARHGAP26

ARHGAP6

AXL

BCOR

BRAF

BRD3

BRD4

CAMTA1

CCNB3

CCND1

CD274

CIC

CRTC1

CSF1

CSF1R

CTNNB1

DNAJB1

EGF

EGFR

EPC1

ERBB2

ERBB4

ERG

ESR1

ESRRA

ETV1

ETV4

ETV5

ETV6

EWSR1

FGF1

FGFR1

FGFR2

FGFR3

FGR

FOS

FOSB

FOXO1

FOXO4

FOXR2

FUS

GLI1

GRB7

HMGA2

HRAS

IDH1

IDH2

IGF1R

INSR

JAK2

JAK3

JAZF1

KRAS

MAML2

MAP2K1

MAST1

MAST2

MBTD1

MDM2

MEAF6

MET

MGEA5

MKL2

MN1

MSMB

MUSK

MYB

MYBL1

MYC

MYOD1

NCOA1

NCOA2

NCOA3

NFATC2

NFE2L2

NFIB

NOTCH1

NOTCH2

NR4A3

NRAS

NRG1

NTRK1

NTRK2

NTRK3

NUMBL

NUTM1

PAX3

PAX8

PDGFB

PDGFD

PDGFRA

PDGFRB

PHF1

PHKB

PIK3CA

PKN1

PLAG1

PPARG

PRDM10

PRKACA

PRKACB

PRKCA

PRKCB

PRKCD

PRKD1

PRKD2

PRKD3

RAD51B

RAF1

RELA

RET

ROS1

RSPO2

RSPO3

SS18

SS18L1

STAT6

TAF15

TCF12

TERT

TFE3

TFEB

TFG

THADA

TMPRSS2

USP6

VGLL2

WWTR1

YAP1

YWHAE

KIT

LEGEND

SNV/Indel
Fusion, splicing or exon-skipping

Need to modify your panel?

Add any of our wet lab-validated designs to this panel with Archer Assay Designer to build an assay that fits your exact requirements.

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For Research Use Only. Not for use in diagnostic procedures.

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For Research Use Only. Not for use in diagnostic procedures.