Comprehensive Thyroid & Lung

The Archer® FusionPlex Comprehensive Thyroid and Lung (CTL) panel is a targeted next-generation sequencing (NGS) product to detect gene fusions, single-nucleotide variant (SNV), indels, splicing and gene expression in 36 genes associated with lung and thyroid cancers. This panel complements the Archer VariantPlex® CTL panel for comprehensive mutation profiling of fusions, copy number variations (CNVs) and variants.

  • Key Features
  • Specifications
  • Gene Targets
  • Additional Resources
Comprehensive Fusion Detection

AMP chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the fusion partner is known.

Splice Variants

Detect cancer-associated isoforms and alternative splicing events.

Low Input

Purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.

Simple, Lyophilized Workflow

Easy-to-handle lyophilized reagents and a simple workflow to minimize errors and reduce turnaround time.

Properties

Specifications

Gene Targets
36
Input cfDNA Required
≤10ng
Unique Molecular On-Target %
>93%
Hands-On Time
2.5 Hour
Total Time
9 Hour
Platform
Illumina® and Ion Torrent™
Sample Types
Fresh frozen and FFPE

Input recommendations for FFPE samples vary depending on Archer PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening

AKT1

ALK

AXL

BRAF

CALCA

CCND1

CTNNB1

DDR2

EGFR

ERBB2

FGFR1

FGFR2

FGFR3

GNAS

HRAS

IDH1

IDH2

KRAS

KRT20

KRT7

MAP2K1

MET

NRAS

NRG1

NTRK1

NTRK2

NTRK3

PIK3CA

PPARG

PTH

RAF1

RET

ROS1

SLC5A5

THADA

TTF1

LEGEND

   SNV/Indel
    Fusion, splicing or exon-skipping
    Expression

 

Product Information
Illumina
  • AB0007 - 8-reactions
  • AB0061 - 48-reactions
  • AB0031 - 16-reactions – Ask about our starter panel
ION TORRENT™
  • AB0010 - 8-reactions
  • AB0062 - 48-reactions
  • AB0030 - 16-reactions – Ask about our starter panel
Archer® Analysis

Need to modify your panel?

Add any of our wet lab-validated designs to this panel with Archer Assay Designer to build an assay that fits your exact requirements.

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For Research Use Only. Not for use in diagnostic procedures.

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For Research Use Only. Not for use in diagnostic procedures.