Comprehensive Thyroid & Lung
The Archer® FusionPlex Comprehensive Thyroid and Lung (CTL) panel is a targeted next-generation sequencing (NGS) product to detect gene fusions, single-nucleotide variant (SNV), indels, splicing and gene expression in 36 genes associated with lung and thyroid cancers. This panel complements the Archer VariantPlex® CTL panel for comprehensive mutation profiling of fusions, copy number variations (CNVs) and variants.
- Key Features
- Specifications
- Gene Targets
- Additional Resources
Comprehensive Fusion Detection
AMP chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the fusion partner is known.
Splice Variants
Detect cancer-associated isoforms and alternative splicing events.
Low Input
Purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.
Simple, Lyophilized Workflow
Easy-to-handle lyophilized reagents and a simple workflow to minimize errors and reduce turnaround time.
Properties
Specifications
Gene Targets
36
Input cfDNA Required
≤10ng
Unique Molecular On-Target %
>93%
Hands-On Time
2.5 Hour
Total Time
9 Hour
Platform
Illumina® and Ion Torrent™
Sample Types
Fresh frozen and FFPE
Input recommendations for FFPE samples vary depending on Archer PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening
AKT1
ALK
AXL
BRAF
CALCA
CCND1
CTNNB1
DDR2
EGFR
ERBB2
FGFR1
FGFR2
FGFR3
GNAS
HRAS
IDH1
IDH2
KRAS
KRT20
KRT7
MAP2K1
MET
NRAS
NRG1
NTRK1
NTRK2
NTRK3
PIK3CA
PPARG
PTH
RAF1
RET
ROS1
SLC5A5
THADA
TTF1
LEGEND
SNV/Indel
Fusion, splicing or exon-skipping
Expression
Product Information
Illumina
- AB0009 - 8-reactions
- AB0061 - 48-reactions
- AB0031 - 16-reactions – Ask about our starter panel
ION TORRENT™
- AB0010 - 8-reactions
- AB0062 - 48-reactions
- AB0030 - 16-reactions – Ask about our starter panel
Archer® Analysis
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