Liquid Biopsy Research

The Archer® LiquidPlex RUO panel for Illumina® is an advanced and user-friendly solution for targeted next-generation sequencing (NGS) of circulating cell-free tumor DNA (ccfDNA/cfDNA/ctDNA) from 28 genes commonly associated with solid tumor type cancers.

  • Key Features
  • Specifications
  • Gene Targets
  • Additional Resources
Relevant Fragment Capture

Anchored Multiplex PCR (AMP™)-based target enrichment preferentially enriches for highly fragmented ctDNA over high molecular weight genomic DNA to reduce background and increase detection sensitivity of low-allele fraction (AF) mutations.

Single-day library prep

NGS-ready libraries can be prepared in under 8 hours with less than 1 hour of hands-on time, providing sequencing results in as little as 3 days.

Error correction & Quantitative Analysis

Molecular barcode sequences ligated prior to amplification enable duplicate read binning and advanced error correction for confident variant calls.

Sensitive & Specific Variant Detection

Reliably detect high AF (5%) variants using as little as 5ng total cfDNA input and low AF (1%) variants from as little as 10ng

Properties

Specifications

Gene Targets
28
Input cfDNA Required
≤5ng
Target Bases Covered
100%
Hands-On Time
1 Hour
Total Time
1 Day
Platform
Illumina
Raw Molecular On-Targe
>90%

AKT1

AKT

AR

BRAF

CTNNB1

DDR2

EGFR

ERBB2

ESR1

FGFR1

HRAS

IDH1

IDH2

KIT

KRAS

MAP2K1

MAP2K2

MET

MTOR

MRAS

NTRK1

NTRK3

PDGFRA

PIK3CA

RET

ROS1

SMAD4

TP53

LEGEND

SNV/Indel

 
Product Information
Illumina
  • AB0088 - 8-reactions
  • AB0090 - 48-reactions
  • AB0106 - 16-reactions- Concordance panel
  • AB0089 - 16-reactions – Ask about our starter panel​​​
Archer® Analysis

Need to modify your panel?

Add any of our wet lab-validated designs to this panel with Archer Assay Designer to build an assay that fits your exact requirements.

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For Research Use Only. Not for use in diagnostic procedures.