Solid Tumor
The VariantPlex Solid Tumor panel is a targeted next-generation sequencing (NGS) product that simultaneously detects and characterizes single-nucleotide variants (SNVs), copy number variations (CNVs) and insertions and deletions (indels) in 67 genes associated with solid tumors.
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- Key Features
- Specifications
- Gene Targets
- Additional Resources
Outlier detection
Molecular barcoded fragment counting provides robust copy number analysis.
Customization
Create from scratch or modify any panel to keep up with the pace of discovery.
Low Input
Anchored Multiplex PCR (AMP™)chemistry was purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.
Simple, Lyophilized Workflow
Easy-to-handle lyophilized reagents and a simple workflow to reduce turnaround time, as well as minimize errors and contamination risk.
Properties
Specifications
Gene Targets
67
Input DNA Required
≤10ng
Total Target Size
~51.0kb
Hands-On Time
2.5 Hour
Total Time
1 Day
Platform
Illumina
Sample Types
Fresh frozen and FFPE
*Input recommendations for FFPE samples vary depending on PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening
ABL1
AKT1
ALK
APC
ATM
AURKA
BRAF
CCND1
CCNE1
CDH1
CDK4
CDKN2A
CSF1R
CTNNB1
DDR2
EGFR
ERBB2
ERBB3
ERBB4
ESR1
EZH2
FBXW7
FGFR1
FGFR2
FGFR3
FLT3
FOXL2
GNA11
GNAQ
GNAS
H3F3A
HNF1A
HRAS
IDH1
IDH2
JAK2
JAK3
KDR
KIT
KRAS
MAP2K1
MDM2
MET
MLH1
MPL
MYC
MYCN
NOTCH1
NPM1
NRAS
PDGFRA
PIK3CA
PIK3R1
PTEN
PTPN11
RB1
RET
RHOA
ROS1
SMAD4
SMARCB1
SMO
SRC
STK11
TERT
TP53
VHL
LEGEND
SNV/Indel CNV
Product Information
Illumina
- SK0111-ILMN-8 - 8-reactions
- SK0111-ILMN 16-reactions Learn More
- Download Protocol
Archer® Analysis
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