Solid Tumor

The Archer® VariantPlex Solid Tumor panel is a targeted next-generation sequencing (NGS) product that simultaneously detects and characterizes single-nucleotide variants (SNVs), copy number variations (CNVs) and insertions and deletions (indels) in 67 genes associated with solid tumors.

  • Key Features
  • Specifications
  • Gene Targets
  • Additional Resources
Quantitative CNV Detection

Molecular barcoded fragment counting provides robust copy number analysis.

Customization

Create from scratch or modify any panel to keep up with the pace of discovery.

Low Input

Anchored Multiplex PCR (AMP™)chemistry was purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.

Simple, Lyophilized Workflow

Easy-to-handle lyophilized reagents and a simple workflow to minimize errors and reduce turnaround time.

Properties

Specifications

Gene Targets
67
Input cfDNA Required
≤10ng
Total Target Size
~51.0kb
Hands-On Time
2.5 Hour
Total Time
1 Day
Platform
Illumina
Sample Types
Fresh frozen and FFPE

+Expected coverage uniformity at the recommended read depth
*Input recommendations for FFPE samples vary depending on Archer PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening

ABL1

AKT1

ALK

APC

ATM

AURKA

BRAF

CCND1

CCNE1

CDH1

CDK4

CDKN2A

CSF1R

CTNNB1

DDR2

EGFR

ERBB2

ERBB3

ERBB4

ESR1

EZH2

FBXW7

FGFR1

FGFR2

FGFR3

FLT3

FOXL2

GNA11

GNAQ

GNAS

H3F3A

HNF1A

HRAS

IDH1

IDH2

JAK2

JAK3

KDR

KIT

KRAS

MAP2K1

MDM2

MET

MLH1

MPL

MYC

MYCN

NOTCH1

NPM1

NRAS

PDGFRA

PIK3CA

PIK3R1

PTEN

PTPN11

RB1

RET

RHOA

ROS1

SMAD4

SMARCB1

SMO

SRC

STK11

TERT

TP53

VHL

LEGEND

SNV/Indel
 CNV

Product Information
Illumina
  • AB0076 - 8-reactions
  • AB0078 - 16-reactions – Ask about our starter panel​​​
Archer® Analysis

Need to modify your panel?

Add any of our wet lab-validated designs to this panel with Archer Assay Designer to build an assay that fits your exact requirements.

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For Research Use Only. Not for use in diagnostic procedures.