Archer DX

VariantPlex

Solid Tumor


The Archer® VariantPlex Solid Tumor panel is a targeted sequencing assay that simultaneously detects and characterizes single-nucleotide variants (SNVs), copy number variations (CNVs) and insertions and deletions (indels) in 67 genes associated with solid tumors.

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Comprehensive Thyroid and Lung


The Archer® VariantPlex Comprehensive Thyroid and Lung (CTL) panel is an next-generation sequencing (NGS)-based targeted sequencing test to detect copy number variations (CNVs), single-nucleotide variants (SNVs) and indels in 31 thyroid and lung cancer-implicated genes. The panel covers entire targeted exons while maintaining high coverage uniformity (> 95%) and on-target reads (99.9%). When used alongside the ribonucleic acid (RNA)-based FusionPlex® CTL panel, fusions, SNVs, CNVs and expression profiles can be analyzed from a single low-input FFPE sample.

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Myeloid


The Archer® VariantPlex Myeloid panel is a 75-gene targeted sequencing panel for acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS) and some lymphoid malignancy markers. Powered by Anchored Multiplex PCR (AMP™) chemistry, the panel enables deep strand-specific amplification of molecular barcoded deoxyribonucleic acid (DNA) fragments for sequencing.

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CFTR


The Archer® VariantPlex CFTR panel is a targeted next-generation sequencing (NGS) test to detect known and unknown variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Independent, unidirectional primers amplify large genomic regions, enabling detection of select intronic variants and exonic mutations as well as large deletions that would otherwise be difficult to detect with opposing primer techniques.

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