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Comprehensive Thyroid & Lung
The VariantPlex Comprehensive Thyroid and Lung (CTL) panel is a targeted next-generation sequencing (NGS) product to detect copy number variations (CNVs), single-nucleotide variants (SNVs) and indels in 31 thyroid and lung cancer-implicated genes. The panel covers entire targeted exons while maintaining high coverage uniformity (> 95%) and on-target reads (99.9%). When used alongside the ribonucleic acid (RNA)-based FusionPlex® CTL panel, fusions, SNVs, CNVs and expression profiles can be analyzed from a single low-input FFPE sample.
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- Key Features
- Specifications
- Gene Targets
- Additional Resources
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Quantitative CNV Detection
Molecular barcoded fragment counting provides robust copy number analysis.
![](https://archerdx.com/wp-content/uploads/2020/06/1_0004_Layer-23.png)
Expert Primer Design
Includes intronic buffers, complete target region coverage and high coverage uniformity.
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Low Input
Anchored Multiplex PCR (AMP™)chemistry was purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue from fine needle aspirates (FNAs).
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Orthogonal Validation
Confirm relevant CNV and SNV calls when using the companion FusionPlex CTL panel.
Properties
Specifications
Gene Targets
31
Input DNA Required
≤10ng
Total Target Size
~21.6kb
Coverage Uniformity >20% mean
>97%
Hands-On Time
2.5 Hour
Total Time
1 Day
Platform
Illumina
Sample Types
Fresh frozen and FFPE
*Input recommendations for FFPE samples vary depending on PreSeq® RNA QC score; 50ng input recommended in absence of PreSeq screening
Product Information
Illumina
- AB0077 - 8-reactions
- AB0081 - 48-reactions
- AB0079 - 16-reactions Learn more
- Download Protocol
Archer® Analysis
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